Progesterone Research Network        

Your Information Source on Bio-Identical Natural Progesterone

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Articles on Pregnancy & Progesterone


I Have Had Several Miscarriages.
Can Natural Progesterone Help Me?

Early miscarriages are becoming more and more frequent.   It will please you to know that the first uses of natural progesterone were in the field of infertility. It was used to help women who had a history of either miscarriages or premature births.

More recent studies have shown that in some women, the surge of progesterone that occurs after they ovulate is not lasting the normal 10-12 days, but is shortened. Without an adequate supply of progesterone to the uterine lining, the survival of the fertilized egg is in jeopardy.  The egg may either not implant at all, or fail to survive after implantation.  This is called “luteal phase failure”.  Having worked for many years for an esteemed infertility specialist in Southern California, I saw this problem a lot.  The woman are getting pregnant, but they are not able to retain the embryo and thus miscarry.

What happens normally after fertilization?  Progesterone production is increased to 30-40 mg. per day immediately.  The level increases gradually until the placenta begins making about 300 mg. of progesterone per day in the 3rd month of pregnancy.

What can this woman do?  She can increase her progesterone levels and maintain them at the level at which they can support a pregnancy.  Many infertility doctors will give a vaginal progesterone suppository.

However, a progesterone creme with a dose of 40 mg. per day can easily supply the necessary progesterone.

If you have been using progesterone in order to get pregnant and you do get pregnant, do not withdraw suddenly from the crème. After 3 months, the placenta makes high amounts of progesterone, therefore after the third month the reduction of natural progesterone should be gradual to avoid any abrupt drop in progesterone levels. 

Women with a history of miscarriage may choose to continue using progesterone through to the week prior to their expected due date.  This gives them peace of mind.

Toxemia during pregnancy: Studies by Dr. Katharine Dalton have concluded that pre-eclampsia, also called toxemia was also helped by the use of progesterone.

Please be sure that the hormone you use during pregnancy is bio-identical natural progesterone, not progestin.  Artificial hormones can be dangerous to the fetus.