Progesterone Research Network        

Your Information Source on Bio-Identical Natural Progesterone

Questions? Call (877) 880-0170                                                                                                                         

Articles on Men's Health / Prostate


            Do You Have a Prostate Problem?


During Urination

  • Do you have to get up at night to urinate?

  • Do you have the sensation of not emptying your bladder completely?

  • After urinating, do you have to do it again in less than two hours?

  • Do you start and stop several times while urinating?

  • Do you sometimes find it difficult to postpone urination?

  • Do you ever have to push or strain to begin urination?

Also,

  • Are you suffering from some degree of impotence?

  • Are your erections becoming less firm?

If you answer "YES" to any of these questions, there's a high probability you have a prostate problem.

If so, you should begin taking steps to immediately bring relief and restore normal function. (Keep in mind that if you're over the age of 45, the odds are 2 to 1 that you'll have problems with your prostate.)


Why does prostate cancer occur so often in aging men?

Consider the changes in testicular hormone production as men age:

1. Testosterone levels fall

2. Testosterone is converted to dihydrotestosterone (DHT) by 5-alpha-reductase enzyme, stimulating prostate growth.

3. Progesterone levels fall

Progesterone is the primary precursor of our adrenal cortical hormones and testosterone. Men synthesize progesterone in smaller amounts than women do, but it is still vital. Since progesterone is a potent inhibitor of 5-alpha-reductase, the decline of progesterone in aging males plays a role in increasing the conversion rate of testosterone to DHT.

4. Estrogen effect increases.

Testosterone is a direct antagonist of estradiol (an estrogen). The effect of estradiol increases when both testosterone levels fall and the shift from testosterone to DHT occurs. Male estradiol levels are equivalent to or sometimes greater than that of postmenopausal females, but normally estradiol's effects are suppressed (antagonized) by the males greater production of testosterone. Estradiol may also be the culprit (along with DHT) in prostate growth.

Thus, progesterone use may counteract both the conversion of testosterone to DHT as well as oppose the estrogen effect.


Sources

Bookhoff H, et al, “Estrogen receptor expression in prostate cancer and pre-malignant prostate lesions,” Am J Pathol 1999; 155: 641-647.

Morgentaler A, Bruning CO et al, “Occult prostate cancer in men with low serum testosterone levels,” JAMA 1996 Dec 18; 276(23):1904-6.

Gustafsson O, Norming U, “Dihydrotestosterone and testosterone levels in men screened for prostate cancer: a study of a randomized population,” Br J Urol. 1996 Mar; 77(3): 433-40. (Karolinska Institue, Stockholm)