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Articles on Osteoporosis


Bone Health Study Graph

According to studies by John R. Lee, M.D. who used natural progesterone in his practice to treat and prevent osteoporosis:

  • Estrogen alone can retard but NOT reverse osteoporosis.

  • Estrogen can not protect against osteoporosis when progesterone is absent.

  • The addition of natural progesterone should be beneficial in preventing or treating premenopausal osteoporosis.

  • Since some estrogen is produced endogenously (within the body) in postmenopausal women, it is possible that supplementation with progesterone alone is sufficient to prevent and/or reverse osteoporosis.

  • Since 1982, Dr. Lee treated postmenopausal osteoporosis with transdermal natural progesterone cream included in a program of diet, mineral and vitamin supplements, and modest exercise, and demonstrated true reversal of osteoporosis even in patients who did not use estrogen supplements.

The graph below illustrates the typical difference in bone mineral density (BMD) changes over a 3-year period between a group of 63 patients. It compares the use of progesterone supplementation, the typical effect of estrogen-only treatment, and the natural course of untreated control patients.

In this graph, it can be seen that:
  • the untreated postmenopausal patient with osteoporosis will lose 1.5% bone mass per year
  • that estrogen-only supplementation will tend to maintain bone mass
  • that only the addition of natural progesterone will increase bone mass, thus reversing the osteoporotic process.