Depression is Widespread
According to the National Institute of Mental
Health (NIMH), every year 9% of U.S adults (19 million people)
have depression. Women are affected twice as often as men, but
depression can strike either sex at any age.
Depression can be devastating. It can make
ordinary tasks seem overwhelming and the usual leisure
activities less enjoyable. Depression may also affect physical
health as mind and body are intertwined.
There are many types of treatments for
depression. These include; counseling, medication and lifestyle
changes. However for many people, the hardest part is reaching
out for help. Doctors and therapists can often help find
solutions if patients ask.
A number of people are exploring alternatives
to conventional antidepressants. For this reason, researchers
have studied DHEA to help combat midlife depression.
About DHEA
DHEA is a naturally occurring steroid hormone
produced by the adrenal glands. It is the precursor of
testosterone and estrogen. Production of DHEA declines in early
adulthood. By age 70, DHEA production is only 20% of that
produced in the 20s.
DHEA supplements are available over the
counter. It is not regulated by the FDA because it is a
supplement, however you should speak to your health care
provider for more information.
DHEA-Depression Study
The DHEA-Depression study was published in
the February edition of the Archives of General Psychiatry. This
small study included 46 subjects, both male and female, age 40
to 65 who suffer from mild-moderate depression. None of the
subjects were taking any other antidepressants and aside from
their depression, were in good health.
Subjects were assigned to take either DHEA or
placebo for 6 weeks. After a 12 week break, the subjects
switched to the other pill (either DHEA or placebo) for 6 more
weeks.
Less Depression with DHEA
Results showed a 50% reduction of depression
symptoms in 23 subjects. Both men and women responded similarly.
DHEA Treatment was also associated with the
following:
DHEA was well tolerated. However the most
common adverse effects include: acne and oily skin
Note: Researchers say that because of the
study’s design, findings don’t apply to severely depressed
individuals and that the long-term effects of DHEA are unknown.
Thus, further studies are needed. However, if you suffer from
depression, you may wish to consult your health care provider
about the use of DHEA.
