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Highlights from the research
of Dr. John Lee
Why Would A Man
Need Supplemental Progesterone?
According to Dr.
Lee, as a male ages, his progesterone level decreases just like
it does in women. In women this decease occurs about the age of
35 and men about ten years later. When progesterone levels
decrease, the male's 5 alpha reductase converts the testosterone
to di-hydro testosterone which is useless at removing the
prostate cancer cells that estradiol stimulates. Estradiol also
stimulates the enlargement of the prostate. This allows the
prostate gland to swell and enlarge and in many cases transform
into prostate cancer.
Do Xenoestrogens
(from the environment) Affect Men?
Men also make
estrogen and estradiol, but in much lower amounts than women.
The male hormone, testosterone, is antagonist to estradiol.
However, estrogen
dominance caused by xenoestrogens is affecting men by raising
their estrogen levels to dangerous levels.
Does Testosterone
Cause Prostate Cancer?
Testosterone does
NOT cause prostate cancer. If this were true 19 and 20 year old
males would be developing prostate cancer as these are the
individuals with the highest levels. This is obviously not the
case, says Dr. Lee.
How Does
Progesterone Protect Against Prostate Cancer?
Dr.Lee tells us
that the prostate is embryologically similar to the female
uterus. Hence it is subject to the estrogen dominance negative
influences, just as the woman’s breast and uterus is. As we
know, progesterone balances or opposes excess estrogen. The
progesterone prevents the body from converting testosterone to
di-hydro testosterone. It does this by inhibiting the enzyme
5-alpha reductase.
Dosage
The dose of
natural progesterone for men is 8 to 10 mg per day. Men do NOT
need time off like women and can take the progesterone without
taking any days off.
Dr. John R. Lee's Research:
Dr. Lee's has a large
number of anecdotal stories of complete reversals of metastatic
prostatic cancers. The clinical research is on-going. There is
strong biochemical evidence to support this recommendation. The
January 28, 1998 Journal of the American Medical Association had an
article To die or not to die? showing that most cells in the body
die through a noninflammatory, energy-dependent form of cell death
called apoptosis. When the apoptosis mechanism is deranged by
mutated cells, a wide array of disease can occur including cancer.
All cells, with the
exception of brain and muscle cells, multiply continuously. The
genes which regulates this cell growth are p53 and bcl2 . If the
gene bcl2 dominates it will push cells to cancer. If gene p53
dominates the opposite will occur and the cell growth is controlled
and the cancer do not occur.
The JAMA article
article clearly shows that traditional chemotherapy using poisons to
stop cell hyperplasia kill normal cells easier than cancer cells.
The new idea promoted by the review is to find agents that activate
p53 and deactivate bc12 in the hope for curing cancer.
Well, the good news
is that research shows that Estradiol (estrogen) turns on the cancer
gene bc12 and progesterone turns on the anti-cancer gene p53!!!
Studies have shown that breast cancer cells do not multiply when
women are on progesterone. These hormones also worked for cancer of
the ovary and uterus and small cell lung cancer which is normally a
very difficult cancer to treat with a horribly dismal diagnosis.
In Summary
Dr. Lee has stated
that nearly all men should seriously consider natural progesterone
replacement sometime in their 40s, or even earlier if they have a
family history of prostate cancer.
ANOTHER NOTE: It has
also been theorized that the use of natural progesterone has a
reasonable likelihood of decreasing male balding, if this is a
benefit of interest to you
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